[Sublingual isosorbide-5 mononitrate during coronary arteriography. Comparison with sublingual nitroglycerin].
| Autor: | Moreira AE; Instituto do Coração do Hospital das Clínicas, FMUSP., Arie S, Costa EL, Campos LF, Soares PR, Garcia DP |
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| Jazyk: | portugalština |
| Zdroj: | Arquivos brasileiros de cardiologia [Arq Bras Cardiol] 1997 Oct; Vol. 69 (4), pp. 247-50. |
| DOI: | 10.1590/s0066-782x1997001000005 |
| Abstrakt: | Purpose: To evaluate the effect of sublingual isosorbide-5 mononitrate (ISMN) and nitroglycerin (NTG) on luminal diameter of epicardial coronary arteries, mean arterial pressure and deleterious effects. Methods: Fifty patients were submitted to cardiac catheterization and coronary arteriography, at baseline, and 5 min after sublingual administration of ISMN, group A (GA) or NTG, group B (GB). Results: Reference vessel diameter increased in both groups, without statistical significance. In GA and GB, a decrease (1.66 mmHg) and an increase (0.79 mmHg) in mean arterial pressure, respectively, were demonstrated (p = 0.123). There were no deleterious effects with the use of these drugs. Conclusion: Sublingual ISMN is an alternative to administration of NTG during coronary arteriography, and represents a therapeutic alternative to ischemic heart disease treatment. |
| Databáze: | MEDLINE |
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