Pregnancies from subzonal insemination of unfertilized oocytes after conventional IVF.
Autor: | Loong EP; Department of Obstetrics and Gynaecology, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong., Chiu TT, Haines CJ |
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Jazyk: | angličtina |
Zdroj: | Chinese medical journal [Chin Med J (Engl)] 1997 Jun; Vol. 110 (6), pp. 479-81. |
Abstrakt: | Objective: To evaluate the efficacy of subzonal insemination (SUZI) as applied to unfertilized oocytes after initial insemination. Methods: Unfertilized oocytes at metaphase II obtained after conventional IVF from 14 patients were selected for reinsemination by SUZI. The fertilization rate and pregnancy outcome were assessed. Results: Of the 57 unfertilized oocytes at metaphase II, 10 (17.5%) became fertilized after SUZI. Eight of the 10 (80%) oocytes showed normal fertilization with two pronuclei while the other two (20%) oocytes were polyspermic. Five (35.7%) of the 14 patients had embryo transfer resulting in two (14.3%) pregnancies. One patient had a spontaneous abortion and the other had a live birth at term. Conclusion: Reinsemination of unfertilized oocytes by SUZI could be of value when fertilization fails after initial insemination. |
Databáze: | MEDLINE |
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