| Autor: |
Paranhos-Silva M; Centro de Pesquisas Gonçalo Moniz, Fundação Oswaldo Cruz, Salvador, Brazil., Nascimento EG, Melro MC, Oliveira GG, dos Santos WL, Pontes-de-Carvalho LC, Oliveira-dos-Santos AJ |
| Jazyk: |
angličtina |
| Zdroj: |
Acta tropica [Acta Trop] 1998 Mar; Vol. 69 (1), pp. 75-83. |
| DOI: |
10.1016/s0001-706x(97)00116-2 |
| Abstrakt: |
American visceral leishmaniasis is a main public health matter in Brazil. Since dogs have been incriminated as the main urban reservoir of AVL agent Leishmania chagasi, a cohort study aimed at understanding the dynamics of the canine infection was carried out in Jequié--an endemic community in the Northeast of Brazil. The inhabited urban and periurban areas of Jequié were divided into 140 clusters of 0.25 km2. All 1681 dogs domiciled in 34 randomly selected clusters were screened for Leishmania antibodies in an enzyme-linked immunosorbent assay. After the seropositive dogs were painlessly eliminated, a cohort of 1286 seronegative dogs was followed up for 18 months, yielding a total of 1739.7 dog-years. The overall incidence of Leishmania infection, as assessed by the detection of Leishmania antibodies in blood samples collected every six months, was 6.55 cases/100 dog-years (95% confidence interval; CI 6.04-7.26). Two subsets of clusters, with 0.70 and 1.35 relative risks of infection, were identified. The annual emigration rate was 2.26 cases/100 dog-years (95% CI 1.86-2.66). The implications of these findings for the control of American visceral leishmaniasis are discussed. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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