[Prevalence of hepatitis D in a population of Northeast Mexico and its relationship with other viruses].

Autor:	Muñoz Espinosa LE; Unidad de Hígado, Facultad de Medicina, Universidad Autónoma de Nuevo León., Ibarra Salas MJ
Jazyk:	Spanish; Castilian
Zdroj:	Revista de gastroenterologia de Mexico [Rev Gastroenterol Mex] 1997 Oct-Dec; Vol. 62 (4), pp. 246-9.
Abstrakt:	Background: There are few reports in Mexico on the prevalence of infection by virus D. Objective: The aim of the present study was to study the hepatitis D virus infection prevalence in patients entering to the University Hospital. Methods: Seventy three HBsAg positive patients sera were studied. There were 38 patients with acute hepatitis, 28 patients with chronic liver disease and 7 were asymptomatic HBsAg carriers. Serological markers for hepatitis viruses B, D and C were detected by means of ELISA test (Abbott). Results: Anti-HDV was detected in 3 cases (4%). The first two cases were men with acute hepatitis B. Both had a coinfection by viruses B and D, however IgM anticore could not be demonstrated in the first case, this patient developed hepatic cirrhosis within 13 months, in addition he had a concurrent infection by hepatitis C virus with a positive second generation ELISA antibody. The second case recovered from the acute hepatitis. The third case was a female nurse with acute hepatitis and a coinfection by viruses B and D who recovered from the acute attack. Antibody to hepatitis C was present in 3 out of 22 patients with chronic liver disease (13.6%), one of them having an hepatocellular carcinoma. Conclusions: Our results coincide with the previously reported low incidence of hepatitis D and represent the first report in Mexico of concurrent infections by viruses B-C and B-D-C.
Databáze:	MEDLINE
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