| Autor: |
Tkachuk ZYu; Institute of Molecular Biology and Genetics, National Academy of Sciences of Ukraine, Kiev., Semernikova LI, Tkachuk VV, Reshot'ko LM, Tkachuk LV, Eremenko T, Matsuka GK, Mikhailopulo IA |
| Jazyk: |
angličtina |
| Zdroj: |
The new microbiologica [New Microbiol] 1998 Apr; Vol. 21 (2), pp. 141-6. |
| Abstrakt: |
The antiviral effect of 2',5'-trioligoadenylate (2',5'-A3) and some of its analogues was studied using several model cell culture systems and viruses: mice L929 fibroblast cells inoculated with vaccine virus, testicular piglet cells inoculated with Aueszki disease virus (strain BUK-628), and the same culture inoculated with a reference strain of transmissible gastroenteritis virus, strain Purdue-115. Our results suggest that both 2',5'-trioligoadenylate and its analogues are promising antiviral substances against DNA- and RNA-containing viruses. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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