| Abstrakt: |
Immunochemical assay for protein composition was made in 22 fertile and 110 subfertile human sperm samples. Changes in the levels of albumin, prostatic acid phosphatase, sperm-specific tripsin inhibitor, prostate-specific antigen and alpha-2-microglobulin of fertility in spermoplasm were studied in different disturbances of ejaculate fecundating ability. The latter was determined by 14 morphofunctional and physicochemical criteria of sperm fertility. With an increase of the ejaculate volume above 5 ml protein homeostasis showed abnormality. The authors consider functional value of the study proteins in ejaculate, pattern of spermatozoid motor activity, maintenance of normal spermoplasmic pH; discuss practical opportunities of the data obtained for increasing fertility of the sperm used in artificial fertilization, diagnosis and treatment of male infertility. |
