Effect of age and hormonal state on cytokine synthesis in the monkey.

Autor: Kaack MB; Department of Urology, Tulane Regional Primate Research Center, Covington, LA 70433, USA., Harrison RM, Roberts JA
Jazyk: angličtina
Zdroj: Cytokine [Cytokine] 1998 Mar; Vol. 10 (3), pp. 236-9.
DOI: 10.1006/cyto.1997.0281
Abstrakt: The authors studied plasma cytokine activity using cross reactive polyclonal antibodies to human cytokines in young and old female monkeys to determine if age had any effect on cytokine secretion, and compared hormonal effects as well. While interleukin 1 (IL-1) was not higher in aged cycling monkeys, it was after menopause. Menopause depressed IL-2 activity also. Variable results were seen with the other cytokines.
Databáze: MEDLINE