Cytodiagnosis of a primary effusion lymphoma. A case report.

Autor: Vadmal MS; Department of Pathology, North Shore University Hospital, Manhasset, New York 11030, USA., Smilari TF, Brody JP, Koduru P, Hajdu SI
Jazyk: angličtina
Zdroj: Acta cytologica [Acta Cytol] 1998 Mar-Apr; Vol. 42 (2), pp. 374-6.
DOI: 10.1159/000331619
Abstrakt: Background: Primary effusion lymphoma (PEL), commonly described in AIDS patients, is a unique subset of lymphoma in which the neoplastic lymphocytes proliferate exclusively in serous cavities.
Case: A 27-year-old male, HIV positive for five years and with multiple opportunistic infections in the past, was admitted for sudden-onset shortness of breath caused by a pleural effusion. Cytologic examination of the pleural fluid revealed medium to large atypical lymphocytes with a high mitosis rate, suspicious for lymphoma. Further diagnostic tests, such as immunophenotypic analysis and cytogenetic and molecular studies, confirmed the diagnosis of PEL.
Conclusion: Cytopathologists and cytotechnologists should be aware of this new entity since additional studies are required for a definitive diagnosis.
Databáze: MEDLINE