| Autor: |
Kazennova EV, Aarons E, Selimova LM, Ladnaia NN, Kravchenko AV, Zhemchugov VE, Chaingon-Popov R, Weber J, Pokrovskiĭ VV, Bobkov AF |
| Jazyk: |
ruština |
| Zdroj: |
Voprosy virusologii [Vopr Virusol] 1998 Jan-Feb; Vol. 43 (1), pp. 30-2. |
| Abstrakt: |
Comparative analysis of the distribution of deletion mutations of CC-chemokine receptor 5 (CCR-5) gene among HIV-1 infected and not infected subjects in Russia showed the incidence of the heterozygous genotype to be 17.8% among both HIV-infected and seronegative subjects. The incidence of the homozygous genotype for the deletion among seronegative individuals was 0.6%, but no homozygotes were found among HIV-1 infected patients. Study of the incidence of the mutant CCR-5 allele among patients infected with different HIV-1 subtypes showed that the susceptibility of heterozygotes to HIV-1 infection was not associated with any special genetic subtype. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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