Translocation t(1;10) (q21;q26) in a case of acute nonlymphocytic leukemia.

Autor: Terreros MC; Servicio de Anatomia Patológica, Hospital Neuropsiquiátrico Especializado Dr. Alejandro Korn, Melchor Romero, La Plata, Argentina. postmaster@anmra.sld.ar, Quesada M, Slavutsky IR
Jazyk: angličtina
Zdroj: Acta haematologica [Acta Haematol] 1998; Vol. 99 (2), pp. 92-4.
DOI: 10.1159/000040818
Abstrakt: Chromosome banding studies carried out on bone marrow cells from a 16 year-old boy with an M1 acute nonlymphocytic leukemia (ANLL) revealed an unbalanced translocation involving chromosomes 1 and 10: der(10) t(1;10) (q21;q26) that results in a partial trisomy 1q between bands 1q21-1qter. Marker del(6)(q21) and trisomies of chromosomes 18, 21 and 22 were also observed. To our knowledge, this der(10) is the first to be reported in a patient with ANLL.
Databáze: MEDLINE