Off-site determinations of effective renal plasma flow using technetium-99m-MAG3 and single blood sampling.

Autor:	Vines D; Department of Nuclear Medicine, Mount Sinai Hospital, Toronto, Ontario, Canada., Denhartog P, Kwan D, Ichise M
Jazyk:	angličtina
Zdroj:	Journal of nuclear medicine technology [J Nucl Med Technol] 1998 Mar; Vol. 26 (1), pp. 23-5.
Abstrakt:	Unlabelled: This study evaluated the feasibility of determining effective renal plasma flow (ERPF) at an off-site central laboratory by transferring blood samples from the on-site laboratory. Methods: Blood samples were obtained from 66 patients referred for renal imaging with 99mTc-MAG3. ERPF values were determined using the single blood sample method (BSM) at both on- and off-site laboratories. The ERPF values were classified clinically as normal or abnormal. Both the ERPF values and clinical classification were compared between on- and off-site laboratories. Results: The off-site ERPF overestimated those on-site by 2.8% (paired Student's t-test p < 10(-5)). However, off-site ERPF values highly correlated with the values obtained on-site (r = 0.99; p < 10(-5)). In addition, the clinical classification for each patient determined at each site was identical. Conclusion: ERPF can be determined accurately off-site. This method should allow many nuclear medicine departments access to the ERPF determination by the BSM at a central off-site laboratory.
Databáze:	MEDLINE
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