| Autor: |
Znoĭko IIu; Kol'tsov Institute of Developmental Biology, Russian Academy of Sciences, Moscow, Russia., Znoĭko SL, Zinov'eva RD, Mitashov VI |
| Jazyk: |
ruština |
| Zdroj: |
Izvestiia Akademii nauk. Seriia biologicheskaia [Izv Akad Nauk Ser Biol] 1997 Nov-Dec (6), pp. 654-9. |
| Abstrakt: |
Differential expression of homeobox genes of the Six family, homologues of Drosophila gene sine oculis, was revealed during limb regeneration of ribbed newt Pleurodeles waltlii and common frog Rana temporaria. Expression of these genes correlated to regeneration capacity in the studied animals. The primary structure of the most conservative region in the identified genes has been determined. We assessed the differences in the primary structure of Six family genes obtained from regenerating limbs of the newt and frog (86 and 94.9% similarity at the nucleotide and amino acid levels, respectively). Comparison of the obtained and published sequences of Six family genes has demonstrated that they are most similar to mouse gene Six1 (84.2 and 82.8% nucleotide sequence similarity in the frog and newt, respectively, and 99.2 and 94.1% amino acid sequence similarity in the frog and newt, respectively. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
