Effect of training on lipid peroxidation, thiol status and antioxidant enzymes in tissues of rats.

Autor: Anuradha CV; Department of Biochemistry, Annamalai University, Nagar., Balakrishnan SD
Jazyk: angličtina
Zdroj: Indian journal of physiology and pharmacology [Indian J Physiol Pharmacol] 1998 Jan; Vol. 42 (1), pp. 64-70.
Abstrakt: The effect of training on lipid peroxidation, thiol-status and certain antioxidant enzymes of glutathione system was studied in blood and tissues such as liver and skeletal muscle of rats. Exercise training was given by subjecting the rats to treadmill running. Training for a period of 6 weeks resulted in increased lipid peroxidation (P < 0.001) as indicated by thiobarbituric acid test and conjugated diene measurement in liver and muscle. Thiol levels (total and non-protein) were reduced. However, glutathione level in blood was increased and blood lipid peroxides were unaltered as a result of training compared to sedentary controls. Adaptive increases in three antioxidant enzyme activities were observed. The study indicates that training induces adaptation in the glutathione system.
Databáze: MEDLINE