Treatment policy after poor fertilization in the first IVF cycle.

Autor: Roest J; Department of Obstetrics and Gynaecology, Zuiderziekenhuis, Rotterdam, The Netherlands., Van Heusden AM, Zeilmaker GH, Verhoeff A
Jazyk: angličtina
Zdroj: Journal of assisted reproduction and genetics [J Assist Reprod Genet] 1998 Jan; Vol. 15 (1), pp. 18-21.
DOI: 10.1023/a:1022570120207
Abstrakt: Purpose: The chance of recurrence of poor fertilization in a second in vitro fertilization (IVF) cycle was assessed.
Methods: Total fertilization failure was defined, and the relationship between the fertilization rate and the number of motile sperm cells per milliliter of semen was assessed. Patients with a total fertilization failure or poor fertilization (20% or less of the oocytes fertilized) were divided into three subgroups with different chances of fertilization and were followed in a subsequent IVF cycle.
Results: The recurrence rate of total fertilization failure was high in all three groups (45-70%), and poor fertilization frequently occurred in the second cycle (50-75%).
Conclusions: Poor fertilization frequently recurs in the second IVF cycle. The use of intracytoplasmic sperm injection could be considered after fertilization of 20% or less of oocytes in the first cycle, irrespective of the number of motile sperm cells per milliliter of semen.
Databáze: MEDLINE
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