Valsalva manoeuvre can be used to study baroreflex sensitivity in pregnancy.

Autor: Ekholm EM; Department of Obstetrics and Gynecology, University of Turku, Finland. eeva.ekholma@tyks.fi, Vesalainen RK, Tahvanainen KU, Kaila T, Erkkola RU
Jazyk: angličtina
Zdroj: European journal of obstetrics, gynecology, and reproductive biology [Eur J Obstet Gynecol Reprod Biol] 1998 Feb; Vol. 76 (2), pp. 153-6.
DOI: 10.1016/s0301-2115(97)00179-6
Abstrakt: Objective: The aim of this study was to assess whether baroreflex sensitivity can be measured in a non-invasive manner with the Valsalva manoeuvre in pregnancy.
Study Design: Baroreflex sensitivity was measured from the reflex response to phenylephrine injection and phase four of the Valsalva manoeuvre in nine pregnant women at 27 (range 24-33) gestational weeks.
Results: Both the phenylephrine test and the Valsalva manoeuvre yielded similar estimates of baroreflex sensitivity (9.3 (4.1) ms/mmHg vs. 8.0 (5.2) ms/mmHg, Pearson's correlation coefficient r = 0.81, P < 0.008, linear regression BRSValsalva (ms/mmHg) = 1.03 x BRSPhenylephrine + 1.59). Comparable changes in heart rate and blood pressure were obtained with the phenylephrine test and the Valsalva manoeuvre.
Conclusion: The physiological challenge caused by the Valsalva manoeuvre can be used to measure baroreflex sensitivity in pregnancy. A possibility to study baroreflex function non-invasively, without pharmacological intervention, benefits future research of blood pressure regulation in pregnancy.
Databáze: MEDLINE
Externí odkaz: