| Autor: |
Spivak MIa, Karpov OV, Antonenko SV, Barbasheva OV, Kvielienkova KI, Voloshchenko IuV |
| Jazyk: |
ukrajinština |
| Zdroj: |
Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993) [Mikrobiol Z] 1997 Sep-Oct; Vol. 59 (5), pp. 57-61. |
| Abstrakt: |
The action of the Bogomolets' antireticular cytotoxic serum (ACS) as a HIV-1 reproduction inhibitor was studied on the model of human lymphoblastoid cell line MT-4/BRU (acute infection). The HIV-1 reproduction inhibition was estimated according to cell protection level for virus cytopathic action and p24 antigen level in the cultural media. The both tests data on ACS usage in dilutions 1:160-1:640 prove that the virus inhibition effect which may be compared with anti-HIV action of the well-known agent, azidothymidine, was observed. At this dilutions range ACS is devoid of the cell toxicity. The conclusion about perspectivity of ACS usage in the AIDS complex therapy was drawn. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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