Autor: |
Tokarskaia ZB; Branch No 1 of Scientific Research Center of Institute of Biophysics, Ozyorsk, Russia., Khokhriakov VF, Okladnikova ND, Beliaeva ZD, Zhuntova GV |
Jazyk: |
ruština |
Zdroj: |
Radiatsionnaia biologiia, radioecologiia [Radiats Biol Radioecol] 1997 Nov-Dec; Vol. 37 (6), pp. 918-25. |
Abstrakt: |
It was shown on the basis of retrospective investigation of 500 workers at a nuclear enterprise (162 cases of lung cancer, 338 persons as matching control) that the interaction of external gamma-irradiation (> 2.0 Gy) and the body-burden of 239Pu (> 9.3 kBq) at lung cancer incidence in multiplicative. Combined influence of smoking and radiation factors was found dependent on smoking index (SI): it changed from additive up to multiplicative and than to antagonistic with the increase of the smoking effect. The received results could be explained on the basis of a two-mutation model of radiation carcinogenesis. |
Databáze: |
MEDLINE |
Externí odkaz: |
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