Autor: |
Edelstein RE; Department of Pediatrics, University of Washington, Seattle, USA., Nickerson DA, Tobe VO, Manns-Arcuino LA, Frenkel LM |
Jazyk: |
angličtina |
Zdroj: |
Journal of clinical microbiology [J Clin Microbiol] 1998 Feb; Vol. 36 (2), pp. 569-72. |
DOI: |
10.1128/JCM.36.2.569-572.1998 |
Abstrakt: |
This report describes the detection of mutations in the pol gene of human immunodeficiency virus type 1 associated with resistance to zidovudine, didanosine, and lamivudine by genotyping by an oligonucleotide ligation assay specific codons in the pol gene amplified by PCR. Our studies demonstrate the sensitivity, simplicity, and specificity of this genotyping system. |
Databáze: |
MEDLINE |
Externí odkaz: |
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