IgM anti-phenolic glycolipid-I antibody measurements from skin-smear sites: correlation with venous antibody levels and the bacterial index.

Autor: Butlin CR; Anandaban Leprosy Hospital, Kathmandu, Nepal., Soares D, Neupane KD, Failbus SS, Roche PW
Jazyk: angličtina
Zdroj: International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association [Int J Lepr Other Mycobact Dis] 1997 Dec; Vol. 65 (4), pp. 465-8.
Abstrakt: Measurements of anti-phenolic glycolipid-I antibodies were made in 200 matched samples of capillary blood from the skin-smear site, venous blood collected on filter paper, and sera. A close correlation among the three samples was observed and a weaker correlation among the antibody levels and the average and skin-smear bacterial index. Capillary blood from the skin-smear site had a consistently higher level of antibodies in each sample than did the sera. The collection of capillary blood from skin-smear sites is a convenient and economical method of obtaining samples for serology and for measuring local antibody levels, and it may be more sensitive than measurements of antibodies in sera.
Databáze: MEDLINE