| Autor: |
Levin BE; Neurology Service (127 C), DVA Medical Center, E. Orange, NJ 07018, USA., Israel P, Lattemann DP |
| Jazyk: |
angličtina |
| Zdroj: |
Brain research bulletin [Brain Res Bull] 1998; Vol. 45 (2), pp. 179-81. |
| DOI: |
10.1016/s0361-9230(97)00336-5 |
| Abstrakt: |
Intracerebroventricular infusion of insulin (2 mU/ day) produced selective downregulation of 3H-paraminoclonidine binding to alpha2-adrenoceptors in the hypothalamic arcuate (14%) and dorsomedial (19%) nuclei out of 16 forebrain areas in Wistar rats. Binding of 3H-prazosin to alpha1-adrenoceptors was unaffected. This is in keeping with the known effect of insulin on catecholamine and neuropeptide Y metabolism in these brain regions that play an important role in energy homeostasis. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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