Autor: |
Musialkovskaia AA, Khodorova EL, Pozdniakova TM |
Jazyk: |
ukrajinština |
Zdroj: |
Ukrains'kyi biokhimichnyi zhurnal [Ukr Biokhim Zh] 1976 Mar-Apr; Vol. 48 (2), pp. 139-43. |
Abstrakt: |
The dimer of fragment D is isolated preparatively by CM-cellulose chromatography (in neutral medium) from dialyzed tryptic hydrolyzate of stabilized fibrin. Contrary to the fragment D monomer obtained from fibrinogen under the same conditions, the dimer itself cannot inhibit polymerization of monomeric fibrin. However with the presence of monomer D in the amount sufficient for essential inhibition of the fibrin polymerization the addition of dimer D produces the further delay in polymerization. Under these conditions dimer D is highly effective inhibitor if its amount is not too little, as its small doses are not effective. |
Databáze: |
MEDLINE |
Externí odkaz: |
|