| Autor: |
Schaefer SL; Laboratory for Comparative Orthopaedic Research, College of Veterinary Medicine, Michigan State University, East Lansing 48824, USA., Ciarelli MJ, Arnoczky SP, Ross HE |
| Jazyk: |
angličtina |
| Zdroj: |
The American journal of sports medicine [Am J Sports Med] 1997 Nov-Dec; Vol. 25 (6), pp. 841-8. |
| DOI: |
10.1177/036354659702500619 |
| Abstrakt: |
The effect of laser energy on the length, stiffness, and structure of connective tissue was examined in a rabbit patellar tendon model. A holmium:yttrium-aluminum-garnet laser was used to deliver a calculated dose of laser energy (300 J/cm2) to one randomly selected patellar tendon in each of 13 adult New Zealand White rabbits. The contralateral patellar tendon was used as a control. Radiopaque markers were placed in the patella and tibial tuberosity to allow for patellar tendon length measurements (via standard lateral radiographs) before and after laser application and at 4 and 8 weeks. Limbs were not immobilized during the postoperative period. The tendons were harvested at 0 weeks (N = 7) and 8 weeks (N = 6) and evaluated for tensile, stiffness, cross-sectional area, histologic changes, and electron microscopic appearance. The results demonstrated significant tendon shrinkage (6.6% +/- 1.4%) after application of the calculated laser energy dose. However, tendon length had increased significantly beyond the immediate postlaser length at 4 weeks and beyond its original length by 8 weeks. At 8 weeks, the lased tendons were significantly less stiff with significantly greater cross-sectional areas than contralateral controls. There was generalized fibroblastic response throughout the entire lased tendon characterized by a marked increase in cellularity. There was also a change from the normal bimodal pattern of large- and small-diameter collagen fibers to a unimodal pattern with predominantly small-diameter fibers in the lased tendons. The tissue alterations seen in this study suggest that the biologic response of connective tissue to laser energy causes a further compromise in tissue integrity, beyond that attributed to the initial physical effects of the laser. These alterations must be taken into consideration when determining postoperative rehabilitation of laser-modified tissues. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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