[Monoarthritis of the knee as an isolated manifestation of paracoccidioidomycosis].

Autor: Silvestre MT; Centro de Ciências Biomédicas, Universidade Federal de Uberlândia, MG., Ferreira MS, Borges AS, Rocha A, de Souza GM, Nishioka SA
Jazyk: portugalština
Zdroj: Revista da Sociedade Brasileira de Medicina Tropical [Rev Soc Bras Med Trop] 1997 Sep-Oct; Vol. 30 (5), pp. 393-5.
DOI: 10.1590/s0037-86821997000500008
Abstrakt: Osteoarthritis in paracoccidioidomycosis has been rarely reported. The present case describes a 36-"year"-old woman, with chronic monoarthritis in the knee lasting 4 years. The diagnosis was achieved only after synovial biopsy, by anatomopathological examination showing granulomatous reaction with a large number of the characteristic "pilot wheel"Paracoccidioides brasiliensis yeast cells. Specific therapy, initially with ketoconazole and followed by cotrimoxazole led to complete functional recovery of the compromised joint. No other affected site was detected by various propaedeutic methods, including computed axial tomography of the thorax and abdomen. The authors emphasize the rarity of the case and discuss its possible pathophysiology.
Databáze: MEDLINE