Mammalian toxicity of helenalin, the toxic principle of Helenium microcephalum CD (smallhead sneezeweed).

Autor: Witzel DA, Ivie W, Dollahite JW
Jazyk: angličtina
Zdroj: American journal of veterinary research [Am J Vet Res] 1976 Jul; Vol. 37 (7), pp. 859-61.
Abstrakt: Studies with smallhead sneezeweed (Helenium microcephalum DC) indicated that a sesquiterpene lactone, helenalin, is the only significant toxic constituent present. The oral median lethal dose of helenalin for 5 mammalian species was between 85 and 105 mg/kg.
Databáze: MEDLINE