| Autor: |
Briko NI, Bovin NV, Shevelev BI, Dynga LO, Blinnikova EI, Kuksiuk PP, Miasoedova SE, Ambrosov IV, Filatov NN |
| Jazyk: |
ruština |
| Zdroj: |
Klinicheskaia laboratornaia diagnostika [Klin Lab Diagn] 1997 Sep (9), pp. 43-6. |
| Abstrakt: |
Enzyme immunoassay kit has been created for detecting antibodies to group A Streptococcus, based on N-acetylglucosamine. N-acetylglucosamine was selected as the group-specific determinant due to the structure of group A Streptococcus polysaccharide, in which this monosaccharide residue is lateral to the main polysaccharide chain and hence more available for antibodies. Water-soluble polyacrylamide is the carrier in this kit, for this carrier is stable and not liable to nonspecific reaction with proteins. In addition, the synthesis of polyacrylamide conjugates ensures reproducible results. Use of this kit permits the identification of group A streptococcal etiology of the disease and thus carry out appropriate therapy; moreover, it helps predict the outcome of an acute streptococcal infection and detect the poststreptococcal complications in the early period of the disease. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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