The maintenance of per-operative mydriasis in phacoemulsification with topical diclofenac sodium.

Autor:	Antcliff RJ; Department of Ophthalmology, Queen Mary's Hospital Sidcup, Sidcup, Kent, UK., Trew DR
Jazyk:	angličtina
Zdroj:	Eye (London, England) [Eye (Lond)] 1997; Vol. 11 ( Pt 3), pp. 389-91.
DOI:	10.1038/eye.1997.82
Abstrakt:	Purpose: To determine whether the use of topical diclofenac sodium (diclofenac) pre-operatively improves the maintenance of per-operative mydriasis, in conjunction with irrigating solutions containing adrenaline. Methods: Sixty-four consecutive patients undergoing phacoemulsification were randomised to receive either diclofenac or no diclofenac in conjunction with cyclopentolate 1% and phenylephrine 10% pre-operatively. They subsequently underwent routine phacoemulsification by one consultant surgeon. Irrigating solutions of balanced salt solution contained adrenaline 1:10(6). Pupil diameters were measured pre-sclerostomy, post-phacoemulsification, post-irrigation/aspiration and on day 1 post-operatively. These were then compared by Student's t-test. Results: The two groups were statistically similar in age and sex. The mean pre-sclerostomy pupillary diameters were 8.1 mm in both groups. The mean post-phacoemulsification diameters were 7.6 mm in those receiving diclofenac and 7.2 mm in those not (p = 0.03). The mean diameters after infusion/aspiration were 7.7 mm in those receiving diclofenac and 7.1 mm in those not (p = 0.008). The mean pupillary diameters on day 1 were 5.3 mm in those receiving diclofenac and 4.6 mm in those not (p = 0.003). Conclusion: Diclofenac improves the maintenance of per-operative mydriasis, in the presence of irrigating solutions containing adrenaline.
Databáze:	MEDLINE
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