Preparation and evaluation of 111In-labeled leukocytes as an abscess imaging agent in dogs.

Autor: Thakur ML, Coleman RE, Mayhall CG, Welch MJ Jr
Jazyk: angličtina
Zdroj: Radiology [Radiology] 1976 Jun; Vol. 119 (3), pp. 731.
DOI: 10.1148/119.3.731
Abstrakt: Leukocytes labeled with 111In chelated with 8-hydroxyquinoline were evaluated as an abscess imaging agent in dogs. The labeling technique is simple and offers 75-95% efficiency. The half-clearance time of the labeled leukocytes is 6-10 hours, and the target-to-blood activity ratios are higher than those of other compounds now in use. The authors suggest that 111In-labeled leukocytes replace 67Ga citrate as a routine abscess imaging agent.
Databáze: MEDLINE