| Autor: |
Seredinin SB, Viglinskaia IV, Kolik LG |
| Jazyk: |
ruština |
| Zdroj: |
Eksperimental'naia i klinicheskaia farmakologiia [Eksp Klin Farmakol] 1997 May-Jun; Vol. 60 (3), pp. 3-5. |
| Abstrakt: |
The effect of the new drug SM-346, a derivative of 2-mercaptobenzimidazole, on the behavior of inbred MR and MNRA rats, differing in the phenotype of the emotional-stress reaction in the open field test was studies. In the Vogel conflict test SM-346 in a dose of 1 mg/kg produced an anxiolytic effect in MR rats but had no effect on the behavior of MNRA rats. The obtained results allow the conclusion that SM-346 possesses a selective anxiolytic action. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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