Desmoplastic fibroma of the temporal bone.
| Autor: | Pensak ML; Department of Otolaryngology, University of Cincinnati College of Medicine, OH 45267-0528, USA., Nestok BR, Van Loveren H, Shumrick KA |
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| Jazyk: | angličtina |
| Zdroj: | The American journal of otology [Am J Otol] 1997 Sep; Vol. 18 (5), pp. 627-31. |
| Abstrakt: | Background: Desmoplastic fibroma is a benign, locally aggressive, intraosseous neoplasm with a propensity for local recurrence. Desmoplastic fibroma most commonly originates within the mandible (70% of cases), and long bones with rare lesions reported in the maxillary, frontal, and parietal bones. We report two patients with desmoplastic fibroma arising within the temporal bone. Study Design: Case report and literature review. Patients: Two patients with desmoplastic fibroma with intracranial and extra cranial growth patterns are presented. Both were young females with aural fullness and decreased hearing. Interventions: Diagnostic and therapeutic. Results: Both tumors were surgically extirpated and the patients have remained disease free for 18-48 months. Neither tumor expressed estrogen or progesterone receptors. Conclusion: Desmoplastic fibroma is a highly invasive local destructive lesion which is best treated by nondestructive surgical intervention. Immunohistochemical analysis may demonstrate hormonal receptors, in which case Tamoxifen may reduce recurrence. |
| Databáze: | MEDLINE |
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