[Basedow's disease in an adolescent with histiocytosis X].

Autor: Viollet L; Service de pédiatrie, hôpital Raymond-Poincaré, Garches, France., Commare-Nordmann MC, Langlais J, Polak M, Donadieu J
Jazyk: francouzština
Zdroj: Archives de pediatrie : organe officiel de la Societe francaise de pediatrie [Arch Pediatr] 1997 Jul; Vol. 4 (7), pp. 656-8.
DOI: 10.1016/s0929-693x(97)83368-4
Abstrakt: Background: Immunological dysfunction is known to be present in Langerhans cell histiocytosis; some autoimmune diseases with autoantibodies associated with this condition have already been described. This immunological dysfunction could play a role in the Langerhans cell histiocytosis pathogenesis.
Case Report: A 13 year-old boy presented a multifocal bone Langerhans cell histiocytosis associated with Graves' syndrome. This last condition was successfully treated with carbimazole while the focal lesions of histiocytosis did not require any treatment.
Conclusion: This unique association could be explained by the immunological dysfunction seen in Langerhans cell histiocytosis with secondary appearance of thyreo-stimulating antibodies.
Databáze: MEDLINE
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