| Autor: |
See Y; Department of Rheumatology, Great Ormond Street Hospital for Sick Children, London., Martin K, Rooney M, Woo P |
| Jazyk: |
angličtina |
| Zdroj: |
British journal of rheumatology [Br J Rheumatol] 1997 Aug; Vol. 36 (8), pp. 912-6. |
| DOI: |
10.1093/rheumatology/36.8.912 |
| Abstrakt: |
We report two boys with juvenile dermatomyositis (JDM) complicated by pancreatitis. One also had hepatitis and probably mild bowel vasculitis, while the other had catastrophic bowel vasculitis with multiple perforations. Both were on corticosteroids, but had features of active vasculitis. The former improved with high-dose i.v. pulsed methylprednisolone, while the latter improved only after immunosuppression with i.v. methylprednisolone, cyclophosphamide and plasmapheresis. Although bowel vasculitis is a known complication of severe JDM, pancreatitis and hepatitis are extremely rare. We have found in a literature search only three other reports of pancreatitis complicating JDM. We wish to alert physicians that pancreatitis may develop in JDM. It should be considered as a differential diagnosis in the child with active disease who develops abdominal pain. Control of vasculitis with adequate immunosuppression, as well as general supportive measures, may be valuable in the treatment of pancreatitis in JDM. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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