| Autor: |
Demaimay F; Laboratoire de Chimie Organique et des Substances Naturelles, Ecole Nationale Supérieure de Chimie de Rennes, France., Noiret N, Roucoux A, Patin H, Bellande E, Pasqualini R, Moisan A |
| Jazyk: |
angličtina |
| Zdroj: |
Nuclear medicine and biology [Nucl Med Biol] 1997 Jul; Vol. 24 (5), pp. 439-45. |
| DOI: |
10.1016/s0969-8051(97)00025-5 |
| Abstrakt: |
Dithiocarboxylate ligands were synthesized and characterised. New nitrido 99m-technetium complexes were obtained with these ligands and identified by thin layer chromatography. The nitrido complexes were tested in vitro in whole blood for leucocyte labelling and the design of the ligand was optimized. Best results were obtained with aliphatic linear ligands, containing 9 to 11 atoms of carbon. The in vivo experiment failed because an inflammated area could not be visualized by gamma imaging, the cell labelling mechanism being probably different. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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