[Postoperative analgesia with epidural methadone in patients operated for hernia of the lumbar disc].

Autor:	Hernández-Palazón J; Servicio de Anestesiologia, Hospital Universitario Virgen de la Arrixaca, Murcia., Tortosa-Serrano JA, Sánchez-Ortega JL, Moya-Solera J, Martínez-Lage JF, Pérez-Flores D
Jazyk:	Spanish; Castilian
Zdroj:	Revista espanola de anestesiologia y reanimacion [Rev Esp Anestesiol Reanim] 1997 May; Vol. 44 (5), pp. 182-5.
Abstrakt:	Objectives: To determine whether the direct application of a single dose of methadone on the dura mater at the end of surgery to repair a lumbar disk hernia provides effective analgesia over the next 24 hours. Patients and Methods: We conducted a randomized double blind study in 40 ASA I patients undergoing elective herniated disk repair under general anesthesia. The sample was divided into two groups (A and B). Group A patients received a solution of methadone in saline solution (5 mg methadone/5 ml saline) applied to the dura before the end of surgery. Group B patients (controls) received only 5 ml of saline. Pain intensity was assessed on a visual analog scale (VAS) during the postoperative period. Also recorded were the observer's impression and the amount of analgesia (ketorolac) consumed through a system providing patient controlled analgesia. Results: Each group contained 20 patients. Group A patients needed significantly less postoperative analgesia (64.2 +/- 14.3 mg) than group B patients (109.6 +/- 16.5 mg). The VAS scores were significantly lower in group A during the first two hours after surgery and were correlated with the observer's impression. No patients suffered serious complications during the study. Conclusions: Topical administration of 5 mg of methadone on the dura mater at the end of herniated lumbar disk repair is an easy, safe and effective technique for providing postoperative analgesia.
Databáze:	MEDLINE
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