Current limitations to protein threading approaches.

Autor: Smith TF; BioMolecular Engineering Research Center, College of Engineering, Boston University, Massachusetts 02215, USA. tsmith@darwin.bu.edu, Lo Conte L, Bienkowska J, Gaitatzes C, Rogers RG Jr, Lathrop R
Jazyk: angličtina
Zdroj: Journal of computational biology : a journal of computational molecular cell biology [J Comput Biol] 1997 Fall; Vol. 4 (3), pp. 217-25.
DOI: 10.1089/cmb.1997.4.217
Abstrakt: A short review of the threading approach to protein structure prediction, including presentation of some open statistical problems. Also discussed is one of the likely sources of the current limited success, that being the form of the pairwise potentials used in most threading approaches.
Databáze: MEDLINE