[The structure of the connective-tissue framework of the skin regenerate in rats during the trypsin and ronidase stimulation of wound healing].

Autor: Surakova TV, Ivanishchuk PP, Mironov AA, Stroganov VA
Jazyk: ruština
Zdroj: Morfologiia (Saint Petersburg, Russia) [Morfologiia] 1997; Vol. 111 (2), pp. 76-9.
Abstrakt: Peculiarities of formation of connective tissue framework of granulation tissue and scar were studied using light optical and scanning electron microscopy in rats during all-layer skin wound healing in interscapular region. Formation of granulation tissue and scar was accelerated after daily 20 minutes treatment with 0.2% trypsin and 0.1% ronidase solutions as compared to that in control. Regenerates are characterized by different morphological properties. Trypsin promotes quick formation of collagen fibre fascicles with their following thickening and gradual exfoliation. Ronidase action leads to small diameter collagen fibres formation and their following organization into larger fascicles. The peculiarities established are associated with different mechanisms of enzyme effect on reparative processes.
Databáze: MEDLINE