| Autor: |
Savinskaya SS, Shekoyan LA, Shirman GA |
| Jazyk: |
angličtina |
| Zdroj: |
Acta virologica [Acta Virol] 1979 May; Vol. 23 (3), pp. 183-8. |
| Abstrakt: |
Antigenic differences between type 1 poliovirus strains circulating in nature were investigated by agar diffusion precipitation reaction. Three strain-specific sera were absorbed with antigens prepared from 8 strains (Sabin's vaccine strain LSc2ab and 7 strains isolated from poliomyelitis patients or healthy persons). The results suggested the presence of at least 5 antigenic determinants in the poliovirus type 1 strains studied. Three determinants in different combinations were found in 7 strains and 2 determinants were found in 1 strain. It is assumed that antigenic differences among poliovirus strains may be due to different combinations of several antigenic determinants. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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