Postoperative hemorrhage associated with carbenicillin administration. Report of two cases and review of the literature.

Autor: Haburchak DR, Head DR, Everett ED
Jazyk: angličtina
Zdroj: American journal of surgery [Am J Surg] 1977 Nov; Vol. 134 (5), pp. 630-4.
DOI: 10.1016/0002-9610(77)90451-2
Abstrakt: Two patients receiving preoperative carbenicillin manifested platelet dysfunction and severe wound hemorrhage. Platelet transfusions appeared beneficial. Investigations indicate that hemostatic abnormalities, especially platelet aggregation defects, may be produced by carbenicillin. Extreme caution and awareness of possible hemorrhage are advised when carbenicillin is used preoperatively.
Databáze: MEDLINE