[Benzopyrene metabolism in cultured liver cells of human embryo].

Autor: Belitskiĭ GA, Eraĭzer TL, Grinberg KN, Kesina AIa
Jazyk: ruština
Zdroj: Voprosy onkologii [Vopr Onkol] 1977; Vol. 23 (6), pp. 69-73.
Abstrakt: The hepatic cells of human embryos cultivated as a monolayer retain their ability to metabolize the carcinogenic hydrocarbon benz (a) pyrene (BP). The intensity of BP metabolism is higher in the "young" cultures of hepatic cells than in fibroblast cultures obtained from the same embryo. At later terms the former becomes equal for both tissues as a result of a decreased metabolic activity of hepatic cells.
Databáze: MEDLINE