| Autor: |
De Groot AS; TB/HIV Research Laboratory, Brown University School of Medicine, Providence, Rhode Island 02912, USA., Jesdale BM, Szu E, Schafer JR, Chicz RM, Deocampo G |
| Jazyk: |
angličtina |
| Zdroj: |
AIDS research and human retroviruses [AIDS Res Hum Retroviruses] 1997 May 01; Vol. 13 (7), pp. 529-31. |
| DOI: |
10.1089/aid.1997.13.529 |
| Abstrakt: |
EpiMatrix/HIV, a tool that is currently available on the World Wide Web, enables researchers to screen HIV proteins for potential MHC ligands. We have performed a comparison of EpiMatrix predictions to 158 published allotype-specific HLA-associated peptides (MHC ligands) derived from 133 proteins. The top 10 ranked EpiMatrix predictions for each of the 158 HLA allotype-protein pairs were selected for comparison with these published ligands. EpiMatrix correctly identified 134 of 158 published ligands (85%). The algorithm is now available for use by the HIV research community at the URL http:/(/)www.EpiMatrix.com/HIV. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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