A color spot test for the detection of Kryptofix 2.2.2 in [18F]FDG preparations.

Autor: Mock BH; Department of Radiology, Indiana University Hospital, Indianapolis 46202-5253, USA. BMOCK@xray.indyrad.iupui.edu, Winkle W, Vavrek MT
Jazyk: angličtina
Zdroj: Nuclear medicine and biology [Nucl Med Biol] 1997 Feb; Vol. 24 (2), pp. 193-5.
DOI: 10.1016/s0969-8051(96)00212-0
Abstrakt: A color spot test is described that can confirm the absence of Kryptofix 2.2.2 in 2-[18F]fluoro-2-deoxy-D-glucose ([18F]FDG) in less than 5 min. Pretreated strips of plastic-backed silica gel 60 thin-layer chromatographic medium, saturated with iodoplatinate reagent, are over-spotted with separate droplets of final product [18F]FDG and Kryptofix standard solutions. A blue-black circular spot is clearly visible at Kryptofix concentrations as low as 2 micrograms/mL.
Databáze: MEDLINE