| Autor: |
Holmblad T; Department of Physiological Botany, University of Uppsala, Sweden., Thörnqvist PO, Söderhäll K, Johansson MW |
| Jazyk: |
angličtina |
| Zdroj: |
The Journal of experimental zoology [J Exp Zool] 1997 Feb 15; Vol. 277 (3), pp. 255-61. |
| Abstrakt: |
We have cloned and sequenced a beta subunit of integrin from a cDNA library of crayfish hemocytes. This beta integrin shows great similarity to beta integrin subunits from other animals; the highest is towards beta pat-3 from Caenorhabditis elegans followed by beta PS from Drosophila melanogaster. By immunoblotting with antibodies raised towards a synthetic peptide corresponding to a part of the cytoplasmic region of the deduced protein sequence, it was shown that the integrin is present in the membrane of the hemocytes. This is the first integrin found in hemocytes of an invertebrate animal and this finding opens the door for further investigations on integrins and their role in the invertebrate immune system. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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