| Autor: |
Yacubian EM; Department of Neurology, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, Brazil., Marie SK, Valério RM, Jorge CL, Yamaga L, Buchpiguel CA |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of neuroimaging : official journal of the American Society of Neuroimaging [J Neuroimaging] 1997 Jan; Vol. 7 (1), pp. 16-22. |
| DOI: |
10.1111/jon19977116 |
| Abstrakt: |
Rasmussen's syndrome is a progressive childhood disease of unknown cause characterized by severe epilepsy, hemiparesis, mental deterioration, inflammation of one cerebral hemisphere, and brain atrophy. Computed tomography, single-photon emission computed tomography (SPECT), and magnetic resonance (MR) neuroimaging findings of 8 patients with pathologically confirmed Rasmussen's syndrome were evaluated retrospectively. All patients showed a predominance of the atrophy in the temporoinsular region and cerebral hemispheric alterations on MR images in a similar extension as seen on SPECT studies. Focal increase in regional cerebral blood flow was observed in the 4 patients presenting with epilepsia partialis continua at the time of hexamethylpropyleneamineoxime injection. Extensive cortical hypoperfusion was noted in the other 4 patients who received the injection during the interictal state. Cerebellar functional abnormalities were present in 6 patients, 2 of them with structural damage. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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