Slow coronary run-off in patients with angina pectoris: clinical significance and thallium-201 scintigraphic study.

Autor: César LA; Instituto do Coração, Faculdade de Medicina, Universidade de São Paulo, Brasil., Ramires JA, Serrano Júnior CV, Meneghetti JC, Antonelli RH, da-Luz PL, Pileggi FJ
Jazyk: angličtina
Zdroj: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas [Braz J Med Biol Res] 1996 May; Vol. 29 (5), pp. 605-13.
Abstrakt: To determine whether or not slow coronary flow (SF) depends on hemodynamic variables, we studied 17 patients (15 men, mean age = 47.8 years) with SF at coronariography. Exercise thallium-201 myocardial scintigraphy revealed perfusion abnormalities in 13 (76.4%) patients. We then selected 89 individuals submitted to cinecoronariography for comparison: 15 were normal and 74 had heart disease. The coronary flow velocity was evaluated by the number of heart beats (HB) needed for coronary artery dye filling. The patients in the SF group had normal hemodynamic variables which were significantly different from those of patients with heart disease (P = 0.001). Patients with heart disease needed no more than 4 HB to fill their arteries, in contrast to 6.88 +/- 1.68 (5 to 11) in the SF group (P < 0.0001). Thus, in our patients with myocardial scintigraphy suggesting ischemia, SF was found to be an event which did not depend on hemodynamic factors.
Databáze: MEDLINE