[Toxicologic study of the antianemia preparation dextrafer].

Autor: Polushina TV, Nemenova NM, Prostakova TM, Zhestkov VA, Sandovnikova SF
Jazyk: ruština
Zdroj: Farmakologiia i toksikologiia [Farmakol Toksikol] 1977 May-Jun; Vol. 40 (3), pp. 366-9.
Abstrakt: Experiments were conduced with a twofold purpose, viz--to determine the medium lethal dose of the preparation and to study the dextrafer distribution in tissues of rabbits after its single or repeated intravenous infusion. The medium lethal dose of the drug was found to be 250 time greater than its maximal therapeutic dose. Morphological and histochemical observations showed dextrafer to have no toxic effect on the rabbits' tissues over a period of 2 years after its single intravenous infusion.
Databáze: MEDLINE