| Autor: |
Cassidy SL; Dow Corning, Health Environmental and Regulatory Affairs, Barry, South Glamorgan., Hale A, Buss DC, Routledge PA |
| Jazyk: |
angličtina |
| Zdroj: |
Human & experimental toxicology [Hum Exp Toxicol] 1997 Jan; Vol. 16 (1), pp. 25-7. |
| DOI: |
10.1177/0960327197016001051 |
| Abstrakt: |
1. The relative binding constants of four drugs to charcoal, silicone oil silicas and acrylate copolymers was studied using an in-vitro binding technique. 2. The maximum adsorption capacity (K2) was chosen as a measure of the degree of binding and calculated by fitting to the Langmuir equation. 3. Charcoal alone was shown to be the most effective of the adsorbents chosen. The possible use of silicone oils as an adsorbent delivery vehicle in treatment of overdose is discussed. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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