[Relationship between hydrogen isotope turnover in tropomyosin and the ionization state of side groups].
| Autor: | Sharf VG, Gabelova NA, Kobiakov VV |
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| Jazyk: | ruština |
| Zdroj: | Biofizika [Biofizika] 1977 Jul-Aug; Vol. 22 (4), pp. 594-8. |
| Abstrakt: | The influence of side group charge of tropomyosin (TM) on hydrogen-deuterium exchange kinetics in wet TM films is shown to depend solely on the change in alpha-helix conformational motility with the charge. For TM films cast from alkaline solutions the less is the positive charge of basic side groups, the higher is found to be conformational motility of both flexible and rigid alpha-helical regions of TM molecules. For TM films cast from acid solutions the conformational motility of the both types of alpha-helices is shown to be the lowest and independent on the charge. |
| Databáze: | MEDLINE |
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