[An EPR study of the joint action of sodium nitrite and whole-body irradiation on animal tissues].

Autor: Kudriavtsev ME, Dmitrieva ON, Kuropteva ZV
Jazyk: ruština
Zdroj: Izvestiia Akademii nauk. Seriia biologicheskaia [Izv Akad Nauk Ser Biol] 1996 Jul-Aug (4), pp. 453-9.
Abstrakt: Changes in metabolic paramagnetic centers of the liver, kidney, spleen, brain and heart tissues, and blood after sodium nitrite intraperitoneal administration irradiation, or combined action of sodium nitrite and irradiation on mice, were studied using the EPR method. It was shown that irradiation of mice after sodium nitrite administration enhanced the effects induced by sodium nitrite alone: the levels of nitrosyl complexes Heme-NO in the tissues, cytochrome P-450 inhibition, and MetHb were higher.
Databáze: MEDLINE