Autor: |
Marchenko VI, Zubanova NA, Diuĭsalieva RG, Voronina FV, Delimbetova GA |
Jazyk: |
ruština |
Zdroj: |
Voprosy virusologii [Vopr Virusol] 1977 Mar-Apr (2), pp. 206-15. |
Abstrakt: |
Experiments revealed parallelism between the duration of the main manifestations of the hyporeactivity phenomenon (tolerance) in interferon induction and the duration of detection of a masked infection with the inducer virus (Newcastle disease virus) in peritoneal exudate cells of tolerant mice. It was also shown that after contact of chick fibroblasts with a dose of interferon which completely inhibited replication of vesicular stomatitis virus infecting the cells this virus was found in the cells in the masked form. Persistence of a virus interferon inducer in the masked form appears to play a significant role in the mechanism of tolerance as well as creation in the interferon-treated cells of conditions for masking viruses infecting these cells. |
Databáze: |
MEDLINE |
Externí odkaz: |
|