Properties of auditory brainstem responses evoked by intra-operative electrical stimulation of the cochlear nucleus in human subjects.

Autor: Waring MD; Electrophysiology Laboratory, House Ear Institute, Los Angeles, CA 90057, USA.
Jazyk: angličtina
Zdroj: Electroencephalography and clinical neurophysiology [Electroencephalogr Clin Neurophysiol] 1996 Nov; Vol. 100 (6), pp. 538-48.
DOI: 10.1016/s0168-5597(96)96061-x
Abstrakt: Electrically evoked auditory brainstem response (EABR) testing can aid placement of the stimulating electrodes during surgical implantation of an auditory brainstem implant (ABI). To facilitate efficient testing, this study of EABR properties examined the effects of various stimulating and recording parameters on the magnitude and clarity of the EABRs obtained from 9 successive ABI patients during intra-operative monitoring. Both stimulus polarities elicited EABRs; the response waveforms were similar and no significant differences between the latencies were found. Stimulus-response relationships displayed thresholds and non-linear growth, characteristic of neural activity, and provided a stimulus amplitude that elicited readily detectable EABRs in all subjects. The stimulus rate could be increased without degrading the EABRs, but usually 50 Hz was used with a 10 ms sampling sweep so that muscle responses, which occurred later than EABRs, could be detected. When 3 stimulating electrodes in a line were tested, the pair with the largest separation consistently provided the largest response. A recording filter passband of 10-3000 Hz was useful for attenuating interference signals because there is negligible energy in the EABR at frequencies above 3 kHz, but there is some energy below 100 Hz.
Databáze: MEDLINE