An outbreak of Burkholderia cepacia lower respiratory tract infection associated with contaminated albuterol nebulization solution.

Autor: Reboli AC; Cooper Hospital/University Medical Center, Division of Infectious Diseases, Camden, NJ 08103, USA., Koshinski R, Arias K, Marks-Austin K, Stieritz D, Stull TL
Jazyk: angličtina
Zdroj: Infection control and hospital epidemiology [Infect Control Hosp Epidemiol] 1996 Nov; Vol. 17 (11), pp. 741-3.
DOI: 10.1086/647220
Abstrakt: An outbreak of Burkholderia cepacia lower respiratory tract colonization and infection occurred in the adult intensive-care units in various geographic locations throughout our hospital. Forty-four patients became colonized or infected over an 11-month period, whereas B cepacia had been isolated from only 13 patients in the preceding 48 months. Environmental cultures revealed the source to be extrinsically contaminated albuterol nebulization solution. Polymerase chain reaction-ribotyping confirmed the genetic relatedness of the B cepacia patient isolates and the contaminated albuterol. After extensive infection control training for the respiratory therapy staff, including attention to nebulization technique, washing and drying the nebulizer cup, and good handwashing, there have not been any new cases.
Databáze: MEDLINE